Protective role of mouse mast cell tryptase Mcpt6 in melanoma

Tryptase‐positive mast cells populate melanomas, but it is not known whether tryptase impacts on melanoma progression. Here we addressed this and show that melanoma growth is significantly higher in tryptase‐deficient (Mcpt6(−/−)) versus wild‐type mice. Histochemical analysis showed that mast cells...

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Detalles Bibliográficos
Autores principales: Grujic, Mirjana, Hellman, Lars, Gustafson, Ann‐Marie, Akula, Srinivas, Melo, Fabio Rabelo, Pejler, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317424/
https://www.ncbi.nlm.nih.gov/pubmed/31894627
http://dx.doi.org/10.1111/pcmr.12859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317424/
https://www.ncbi.nlm.nih.gov/pubmed/31894627
http://dx.doi.org/10.1111/pcmr.12859

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