Tuning Enzyme Activity for Nonaqueous Solvents: Engineering an Enantioselective “Michaelase” for Catalysis in High Concentrations of Ethanol

Enzymes have evolved to function under aqueous conditions and may not exhibit features essential for biocatalytic application, such as the ability to function in high concentrations of an organic solvent. Consequently, protein engineering is often required to tune an enzyme for catalysis in non‐aque...

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Detalles Bibliográficos
Autores principales: Guo, Chao, Biewenga, Lieuwe, Lubberink, Max, van Merkerk, Ronald, Poelarends, Gerrit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317446/
https://www.ncbi.nlm.nih.gov/pubmed/31886617
http://dx.doi.org/10.1002/cbic.201900721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317446/
https://www.ncbi.nlm.nih.gov/pubmed/31886617
http://dx.doi.org/10.1002/cbic.201900721

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