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Oridonin ameliorates carbon tetrachloride‐induced liver fibrosis in mice through inhibition of the NLRP3 inflammasome

Liver fibrosis is characterized by the activation of hepatic stellate cells (HSCs) and accumulation of the extracellular matrix. There are limitations in the current therapies for liver fibrosis. Recently, oridonin was shown to induce apoptosis in HSCs. Thus, we aimed to determine the roles of orido...

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Detalles Bibliográficos
Autores principales: Liu, Dong, Qin, Hailong, Yang, Bixian, Du, Bin, Yun, Xuelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317507/
https://www.ncbi.nlm.nih.gov/pubmed/32219880
http://dx.doi.org/10.1002/ddr.21649