Cargando…

A Novel Visible Range FRET Probe for Monitoring Acid Sphingomyelinase Activity in Living Cells

Activity of acid sphingomyelinase has been implicated in a number of diseases like acute lung injury, sepsis or metastasis of melanoma cells. Here, we present a sphingomyelinase FRET probe based on FAM/BODIPY dyes for real‐time monitoring of acid sphingomyelinase. The probe gives rise to a tremendou...

Descripción completa

Detalles Bibliográficos
Autores principales: Kappe, Christian, Mohamed, Zainelabdeen H., Naser, Eyad, Carpinteiro, Alexander, Arenz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317515/
https://www.ncbi.nlm.nih.gov/pubmed/32092185
http://dx.doi.org/10.1002/chem.202000133