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Absence of Bsep/Abcb11 attenuates MCD diet‐induced hepatic steatosis but aggravates inflammation in mice
BACKGROUND: Bile acids (BAs) regulate hepatic lipid metabolism and inflammation. Bile salt export pump (BSEP) KO mice are metabolically preconditioned with a hydrophilic BA composition protecting them from cholestasis. We hypothesize that changes in hepatic BA profile and subsequent changes in BA si...
Autores principales: | Fuchs, Claudia D., Krivanec, Sebastian, Steinacher, Daniel, Mlitz, Veronika, Wahlström, Annika, Stahlman, Marcus, Claudel, Thierry, Scharnagl, Hubert, Stojakovic, Tatjana, Marschall, Hanns‐Ulrich, Trauner, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317533/ https://www.ncbi.nlm.nih.gov/pubmed/32141703 http://dx.doi.org/10.1111/liv.14423 |
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