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High tumor mutation burden predicts favorable outcome among patients with aggressive histological subtypes of lung adenocarcinoma: A population-based single-institution study

OBJECTIVES: Tumor mutation burden (TMB) is an emerging predictive cancer biomarker. Few studies have addressed the prognostic role of TMB in non-small cell lung carcinoma, with conflicting results. Moreover, the association of TMB with different histological subtypes of lung adenocarcinoma has hithe...

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Detalles Bibliográficos
Autores principales: Talvitie, Eva-Maria, Vilhonen, Heikki, Kurki, Samu, Karlsson, Antti, Orte, Katri, Almangush, Alhadi, Mohamed, Hesham, Liljeroos, Lassi, Singh, Yajuvinder, Leivo, Ilmo, Laitinen, Tarja, Kallajoki, Markku, Taimen, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317687/
https://www.ncbi.nlm.nih.gov/pubmed/32585428
http://dx.doi.org/10.1016/j.neo.2020.05.004

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