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Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin‐1 binding of small molecules
Neuropilin‐1 (NRP1) is emerging as an important molecule in immune signaling where it has been shown to modulate the actions of TGF‐β1 in macrophages and regulatory T cells. The development of cost‐effective and reliable assays for NRP1 binding is therefore important. We synthesized three new NRP1 s...
Autores principales: | Conole, Daniel, Chou, Yi‐Tai, Patsiarika, Anastasia, Nwabo, Valery, Dimitriou, Eleni, Soudy, Christelle, Mota, Filipa, Djordjevic, Snezana, Selwood, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317715/ https://www.ncbi.nlm.nih.gov/pubmed/31958155 http://dx.doi.org/10.1002/ddr.21641 |
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