V(H)‐V(L) interdomain dynamics observed by computer simulations and NMR

The relative orientation of the two variable domains, V(H) and V(L), influences the shape of the antigen binding site, that is, the paratope, and is essential to understand antigen specificity. ABangle characterizes the V(H)‐V(L) orientation by using five angles and a distance and compares it to oth...

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Detalles Bibliográficos
Autores principales: Fernández‐Quintero, Monica L., Hoerschinger, Valentin J., Lamp, Leonida M., Bujotzek, Alexander, Georges, Guy, Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317758/
https://www.ncbi.nlm.nih.gov/pubmed/31904133
http://dx.doi.org/10.1002/prot.25872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317758/
https://www.ncbi.nlm.nih.gov/pubmed/31904133
http://dx.doi.org/10.1002/prot.25872

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