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V(H)‐V(L) interdomain dynamics observed by computer simulations and NMR
The relative orientation of the two variable domains, V(H) and V(L), influences the shape of the antigen binding site, that is, the paratope, and is essential to understand antigen specificity. ABangle characterizes the V(H)‐V(L) orientation by using five angles and a distance and compares it to oth...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317758/ https://www.ncbi.nlm.nih.gov/pubmed/31904133 http://dx.doi.org/10.1002/prot.25872 |