Cargando…
On the localization of the cleavage site in human alpha‐2‐antiplasmin, involved in the generation of the non‐plasminogen binding form
BACKGROUND: Alpha‐2‐antiplasmin (α2AP) is the main natural inhibitor of plasmin. The C‐terminus of α2AP is crucial for the initial interaction with plasmin(ogen) and the rapid inhibitory mechanism. Approximately 35% of circulating α2AP has lost its C‐terminus (non‐plasminogen binding α2AP/NPB‐α2AP)...
Autores principales: | Abdul, Shiraazkhan, Dekkers, Dick H. W., Ariëns, Robert A. S., Leebeek, Frank W. G., Rijken, Dingeman C., Uitte de Willige, Shirley |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317795/ https://www.ncbi.nlm.nih.gov/pubmed/32034861 http://dx.doi.org/10.1111/jth.14761 |
Ejemplares similares
-
Generation and characterization of monoclonal antibodies against the N-terminus of alpha-2-antiplasmin
por: Abdul, Shiraazkhan, et al.
Publicado: (2018) -
Increased urokinase and consumption of α(2)‐antiplasmin as an explanation for the loss of benefit of tranexamic acid after treatment delay
por: Longstaff, C., et al.
Publicado: (2018) -
Inhibition of Fibrinolysis by Coagulation Factor XIII
por: Rijken, Dingeman C., et al.
Publicado: (2017) -
Hindered dissolution of fibrin formed under mechanical stress
por: Varjú, I, et al.
Publicado: (2011) -
Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysis
por: Mutch, N J, et al.
Publicado: (2010)