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Organophotocatalytic N‐Demethylation of Oxycodone Using Molecular Oxygen

N‐Demethylation of oxycodone is one of the key steps in the synthesis of important opioid antagonists like naloxone or analgesics like nalbuphine. The reaction is typically carried out using stoichiometric amounts of toxic and corrosive reagents. Herein, we present a green and scalable organophotoca...

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Detalles Bibliográficos
Autores principales: Chen, Yuesu, Glotz, Gabriel, Cantillo, David, Kappe, C. Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317935/
https://www.ncbi.nlm.nih.gov/pubmed/31898822
http://dx.doi.org/10.1002/chem.201905505

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