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Organophotocatalytic N‐Demethylation of Oxycodone Using Molecular Oxygen
N‐Demethylation of oxycodone is one of the key steps in the synthesis of important opioid antagonists like naloxone or analgesics like nalbuphine. The reaction is typically carried out using stoichiometric amounts of toxic and corrosive reagents. Herein, we present a green and scalable organophotoca...
Autores principales: | Chen, Yuesu, Glotz, Gabriel, Cantillo, David, Kappe, C. Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317935/ https://www.ncbi.nlm.nih.gov/pubmed/31898822 http://dx.doi.org/10.1002/chem.201905505 |
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