Circuit Topology Analysis of Polymer Folding Reactions

[Image: see text] Circuit topology is emerging as a versatile measure to classify the internal structures of folded linear polymers such as proteins and nucleic acids. The topology framework can be applied to a wide range of problems, most notably molecular folding reactions that are central to biol...

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Autores principales: Heidari, Maziar, Schiessel, Helmut, Mashaghi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318069/
https://www.ncbi.nlm.nih.gov/pubmed/32607431
http://dx.doi.org/10.1021/acscentsci.0c00308
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author Heidari, Maziar
Schiessel, Helmut
Mashaghi, Alireza
author_facet Heidari, Maziar
Schiessel, Helmut
Mashaghi, Alireza
author_sort Heidari, Maziar
collection PubMed
description [Image: see text] Circuit topology is emerging as a versatile measure to classify the internal structures of folded linear polymers such as proteins and nucleic acids. The topology framework can be applied to a wide range of problems, most notably molecular folding reactions that are central to biology and molecular engineering. In this Outlook, we discuss the state-of-the art of the technology and elaborate on the opportunities and challenges that lie ahead.
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spelling pubmed-73180692020-06-29 Circuit Topology Analysis of Polymer Folding Reactions Heidari, Maziar Schiessel, Helmut Mashaghi, Alireza ACS Cent Sci [Image: see text] Circuit topology is emerging as a versatile measure to classify the internal structures of folded linear polymers such as proteins and nucleic acids. The topology framework can be applied to a wide range of problems, most notably molecular folding reactions that are central to biology and molecular engineering. In this Outlook, we discuss the state-of-the art of the technology and elaborate on the opportunities and challenges that lie ahead. American Chemical Society 2020-05-12 2020-06-24 /pmc/articles/PMC7318069/ /pubmed/32607431 http://dx.doi.org/10.1021/acscentsci.0c00308 Text en Copyright © 2020 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Heidari, Maziar
Schiessel, Helmut
Mashaghi, Alireza
Circuit Topology Analysis of Polymer Folding Reactions
title Circuit Topology Analysis of Polymer Folding Reactions
title_full Circuit Topology Analysis of Polymer Folding Reactions
title_fullStr Circuit Topology Analysis of Polymer Folding Reactions
title_full_unstemmed Circuit Topology Analysis of Polymer Folding Reactions
title_short Circuit Topology Analysis of Polymer Folding Reactions
title_sort circuit topology analysis of polymer folding reactions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318069/
https://www.ncbi.nlm.nih.gov/pubmed/32607431
http://dx.doi.org/10.1021/acscentsci.0c00308
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