Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function

Regulatory T cells (Treg cells) are essential for maintaining immune tolerance, and the dysfunction of Treg cells may cause autoimmune diseases and tumors. Forkhead box P3 (FOXP3) is the key transcription factor controlling Treg cell development and suppressive function. Mouse double minute 2 homolo...

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Detalles Bibliográficos
Autores principales: Wang, Aiting, Yang, Mengdi, Liang, Rui, Zhu, Fangming, Zhu, Fuxiang, Liu, Xinnan, Han, Yichao, Lin, Ruirong, Wang, Xiaoxia, Li, Dan, Li, Hecheng, Yuan, Xiaojun, Zhao, Hui, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318079/
https://www.ncbi.nlm.nih.gov/pubmed/32636834
http://dx.doi.org/10.3389/fimmu.2020.01087

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