An evolutionary framework for treating pediatric sarcomas

Lessons from extinction can be used in trials designed to pursue a cure for cancer. When cancer cannot be cured, similar strategies may be unwise, and strategies that leverage the adaptations of cancer to therapy should be considered.

Detalles Bibliográficos
Autores principales: Reed, Damon R., Metts, Jonathan, Pressley, Mariyah, Fridley, Brooke L., Hayashi, Masanori, Isakoff, Michael S., Loeb, David M., Makanji, Rikesh, Roberts, Ryan D., Trucco, Matteo, Wagner, Lars M., Alexandrow, Mark G., Gatenby, Robert A., Brown, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318114/
https://www.ncbi.nlm.nih.gov/pubmed/32176331
http://dx.doi.org/10.1002/cncr.32777
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author Reed, Damon R.
Metts, Jonathan
Pressley, Mariyah
Fridley, Brooke L.
Hayashi, Masanori
Isakoff, Michael S.
Loeb, David M.
Makanji, Rikesh
Roberts, Ryan D.
Trucco, Matteo
Wagner, Lars M.
Alexandrow, Mark G.
Gatenby, Robert A.
Brown, Joel S.
author_facet Reed, Damon R.
Metts, Jonathan
Pressley, Mariyah
Fridley, Brooke L.
Hayashi, Masanori
Isakoff, Michael S.
Loeb, David M.
Makanji, Rikesh
Roberts, Ryan D.
Trucco, Matteo
Wagner, Lars M.
Alexandrow, Mark G.
Gatenby, Robert A.
Brown, Joel S.
author_sort Reed, Damon R.
collection PubMed
description Lessons from extinction can be used in trials designed to pursue a cure for cancer. When cancer cannot be cured, similar strategies may be unwise, and strategies that leverage the adaptations of cancer to therapy should be considered.
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spelling pubmed-73181142020-06-29 An evolutionary framework for treating pediatric sarcomas Reed, Damon R. Metts, Jonathan Pressley, Mariyah Fridley, Brooke L. Hayashi, Masanori Isakoff, Michael S. Loeb, David M. Makanji, Rikesh Roberts, Ryan D. Trucco, Matteo Wagner, Lars M. Alexandrow, Mark G. Gatenby, Robert A. Brown, Joel S. Cancer Commentary Lessons from extinction can be used in trials designed to pursue a cure for cancer. When cancer cannot be cured, similar strategies may be unwise, and strategies that leverage the adaptations of cancer to therapy should be considered. John Wiley and Sons Inc. 2020-03-16 2020-06-01 /pmc/articles/PMC7318114/ /pubmed/32176331 http://dx.doi.org/10.1002/cncr.32777 Text en © 2020 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Commentary
Reed, Damon R.
Metts, Jonathan
Pressley, Mariyah
Fridley, Brooke L.
Hayashi, Masanori
Isakoff, Michael S.
Loeb, David M.
Makanji, Rikesh
Roberts, Ryan D.
Trucco, Matteo
Wagner, Lars M.
Alexandrow, Mark G.
Gatenby, Robert A.
Brown, Joel S.
An evolutionary framework for treating pediatric sarcomas
title An evolutionary framework for treating pediatric sarcomas
title_full An evolutionary framework for treating pediatric sarcomas
title_fullStr An evolutionary framework for treating pediatric sarcomas
title_full_unstemmed An evolutionary framework for treating pediatric sarcomas
title_short An evolutionary framework for treating pediatric sarcomas
title_sort evolutionary framework for treating pediatric sarcomas
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318114/
https://www.ncbi.nlm.nih.gov/pubmed/32176331
http://dx.doi.org/10.1002/cncr.32777
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