Cargando…

Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients

Suction of the left ventricle can lead to potentially life‐threatening events in left ventricular assist device (LVAD) patients. With the resolution of currently available clinical LVAD monitoring healthcare professionals are unable to evaluate patients’ suction occurrences in detail. This study inv...

Descripción completa

Detalles Bibliográficos
Autores principales: Gross, Christoph, Schima, Heinrich, Schlöglhofer, Thomas, Dimitrov, Kamen, Maw, Martin, Riebandt, Julia, Wiedemann, Dominik, Zimpfer, Daniel, Moscato, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318142/
https://www.ncbi.nlm.nih.gov/pubmed/31945201
http://dx.doi.org/10.1111/aor.13638
_version_ 1783550777658179584
author Gross, Christoph
Schima, Heinrich
Schlöglhofer, Thomas
Dimitrov, Kamen
Maw, Martin
Riebandt, Julia
Wiedemann, Dominik
Zimpfer, Daniel
Moscato, Francesco
author_facet Gross, Christoph
Schima, Heinrich
Schlöglhofer, Thomas
Dimitrov, Kamen
Maw, Martin
Riebandt, Julia
Wiedemann, Dominik
Zimpfer, Daniel
Moscato, Francesco
author_sort Gross, Christoph
collection PubMed
description Suction of the left ventricle can lead to potentially life‐threatening events in left ventricular assist device (LVAD) patients. With the resolution of currently available clinical LVAD monitoring healthcare professionals are unable to evaluate patients’ suction occurrences in detail. This study investigates occurrences and durations of suction events and their associations with tachycardia in stable outpatients. Continuous high‐resolution LVAD data from HVAD patients were analyzed in the early outpatient period for 15 days. A validated suction detection from LVAD signals was used. Suction events were evaluated as suction rates, bursts of consecutive suction beats, and clusters of suction beats. The occurrence of tachycardia was analyzed before, during, and after suction clusters. Furthermore, blood work, implant strategy, LVAD speed setting, inflow cannula position, left ventricular diameters, and adverse events were evaluated in these patients. LVAD data of 10 patients was analyzed starting at 78 ± 22 postoperative days. Individuals’ highest suction rates per hour resulted in a median of 11% (range 3%‐61%). Bursts categorized as consecutive suction beats with n = 2, n = 3‐5, n = 6‐15, and n > 15 beats were homogenously distributed with 10.3 ± 0.8% among all suction beats. Larger suction bursts were followed by shorter suction‐free periods. Tachycardia during suction occurred in 12% of all suction clusters. Significant differences in clinical parameters between individuals with high and low suction rates were only observed in left ventricular end‐diastolic and end‐systolic diameters (P < .02). Continuous high‐resolution LVAD monitoring sheds light on outpatient suction occurrences. Interindividual and intraindividual characteristics of longitudinal suction rates were observed. Longer suction clusters have higher probabilities of tachycardia within the cluster and more severe types of suction waveforms. This work shows the necessity of improved LVAD monitoring and the implementation of an LVAD speed control to reduce suction rates and their concomitant burden on the cardiovascular system.
format Online
Article
Text
id pubmed-7318142
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-73181422020-06-29 Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients Gross, Christoph Schima, Heinrich Schlöglhofer, Thomas Dimitrov, Kamen Maw, Martin Riebandt, Julia Wiedemann, Dominik Zimpfer, Daniel Moscato, Francesco Artif Organs Electronic‐only Articles Suction of the left ventricle can lead to potentially life‐threatening events in left ventricular assist device (LVAD) patients. With the resolution of currently available clinical LVAD monitoring healthcare professionals are unable to evaluate patients’ suction occurrences in detail. This study investigates occurrences and durations of suction events and their associations with tachycardia in stable outpatients. Continuous high‐resolution LVAD data from HVAD patients were analyzed in the early outpatient period for 15 days. A validated suction detection from LVAD signals was used. Suction events were evaluated as suction rates, bursts of consecutive suction beats, and clusters of suction beats. The occurrence of tachycardia was analyzed before, during, and after suction clusters. Furthermore, blood work, implant strategy, LVAD speed setting, inflow cannula position, left ventricular diameters, and adverse events were evaluated in these patients. LVAD data of 10 patients was analyzed starting at 78 ± 22 postoperative days. Individuals’ highest suction rates per hour resulted in a median of 11% (range 3%‐61%). Bursts categorized as consecutive suction beats with n = 2, n = 3‐5, n = 6‐15, and n > 15 beats were homogenously distributed with 10.3 ± 0.8% among all suction beats. Larger suction bursts were followed by shorter suction‐free periods. Tachycardia during suction occurred in 12% of all suction clusters. Significant differences in clinical parameters between individuals with high and low suction rates were only observed in left ventricular end‐diastolic and end‐systolic diameters (P < .02). Continuous high‐resolution LVAD monitoring sheds light on outpatient suction occurrences. Interindividual and intraindividual characteristics of longitudinal suction rates were observed. Longer suction clusters have higher probabilities of tachycardia within the cluster and more severe types of suction waveforms. This work shows the necessity of improved LVAD monitoring and the implementation of an LVAD speed control to reduce suction rates and their concomitant burden on the cardiovascular system. John Wiley and Sons Inc. 2020-03-01 2020-07 /pmc/articles/PMC7318142/ /pubmed/31945201 http://dx.doi.org/10.1111/aor.13638 Text en © 2020 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Electronic‐only Articles
Gross, Christoph
Schima, Heinrich
Schlöglhofer, Thomas
Dimitrov, Kamen
Maw, Martin
Riebandt, Julia
Wiedemann, Dominik
Zimpfer, Daniel
Moscato, Francesco
Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients
title Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients
title_full Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients
title_fullStr Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients
title_full_unstemmed Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients
title_short Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients
title_sort continuous lvad monitoring reveals high suction rates in clinically stable outpatients
topic Electronic‐only Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318142/
https://www.ncbi.nlm.nih.gov/pubmed/31945201
http://dx.doi.org/10.1111/aor.13638
work_keys_str_mv AT grosschristoph continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients
AT schimaheinrich continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients
AT schloglhoferthomas continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients
AT dimitrovkamen continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients
AT mawmartin continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients
AT riebandtjulia continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients
AT wiedemanndominik continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients
AT zimpferdaniel continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients
AT moscatofrancesco continuouslvadmonitoringrevealshighsuctionratesinclinicallystableoutpatients