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Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2

NK cells are innate lymphocytes responsible for lysis of pathogen‐infected and transformed cells. One of the major activating receptors required for target cell recognition is the NK group 2D (NKG2D) receptor. Numerous reports show the necessity of NKG2D for effective tumor immune surveillance. Furt...

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Detalles Bibliográficos
Autores principales:	Prinz, Daniela, Klein, Klara, List, Julia, Knab, Vanessa M., Menzl, Ingeborg, Leidenfrost, Nicoletta, Heller, Gerwin, Polić, Bojan, Putz, Eva Maria, Witalisz‐Siepracka, Agnieszka, Sexl, Veronika, Gotthardt, Dagmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Tumor immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318224/ https://www.ncbi.nlm.nih.gov/pubmed/32052406 http://dx.doi.org/10.1002/eji.201948222

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