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Synthesis of Small‐Molecule Fluorescent Probes for the In Vitro Imaging of Calcium‐Activated Potassium Channel K(Ca)3.1

Small‐molecule probes for the in vitro imaging of K(Ca)3.1 channel‐expressing cells were developed. Senicapoc, showing high affinity and selectivity for the K(Ca)3.1 channels, was chosen as the targeting component. BODIPY dyes 15–20 were synthesized and connected by a Cu(I)‐catalyzed azide–alkyne [3...

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Detalles Bibliográficos
Autores principales:	Brömmel, Kathrin, Maskri, Sarah, Maisuls, Ivan, Konken, Christian Paul, Rieke, Marius, Pethő, Zoltan, Strassert, Cristian A., Koch, Oliver, Schwab, Albrecht, Wünsch, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318252/ https://www.ncbi.nlm.nih.gov/pubmed/32097518 http://dx.doi.org/10.1002/anie.202001201

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