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In Situ Acetaldehyde Synthesis for Carboligation Reactions

The enzyme 4‐oxalocrotonate tautomerase (4‐OT) can promiscuously catalyze various carboligation reactions using acetaldehyde as a nucleophile. However, the highly reactive nature of acetaldehyde requires intricate handling, which can impede its usage in practical synthesis. Therefore, we investigate...

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Detalles Bibliográficos
Autores principales:	Biewenga, Lieuwe, Kunzendorf, Andreas, Poelarends, Gerrit J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318290/ https://www.ncbi.nlm.nih.gov/pubmed/31868962 http://dx.doi.org/10.1002/cbic.201900666

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