A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity

The limited efficacy of seasonal influenza vaccines is usually attributed to ongoing variation in the major antigenic targets for protective antibody responses including hemagglutinin (HA) and neuraminidase (NA). Hence, vaccine development has largely focused on broadening antigenic epitopes to gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato-Kaneko, Fumi, Yao, Shiyin, Lao, Fitzgerald S., Shpigelman, Jonathan, Messer, Karen, Pu, Minya, Shukla, Nikunj M., Cottam, Howard B., Chan, Michael, Chu, Paul J., Burkhart, David, Schoener, Roman, Matsutani, Takaji, Carson, Dennis A., Corr, Maripat, Hayashi, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318308/
https://www.ncbi.nlm.nih.gov/pubmed/32636840
http://dx.doi.org/10.3389/fimmu.2020.01207

Ejemplares similares

Ejemplares similares