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Metabolic regulation of hepatic PNPLA3 expression and severity of liver fibrosis in patients with NASH

BACKGROUND AND AIMS: The genetic PNPLA3 polymorphism I148M has been extensively associated with higher risk for development and progression of NAFLD towards NASH. METHODS: PNPLA3 and α‐SMA expression were quantified in liver biopsies collected from NASH patients (n = 26) with different fibrosis stag...

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Detalles Bibliográficos
Autores principales:	Bruschi, Francesca V., Tardelli, Matteo, Herac, Merima, Claudel, Thierry, Trauner, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Metabolic & Toxic Liver Diseases
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318357/ https://www.ncbi.nlm.nih.gov/pubmed/32043752 http://dx.doi.org/10.1111/liv.14402

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