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KinCon: Cell‐based recording of full‐length kinase conformations

The spectrum of kinase alterations displays distinct functional characteristics and requires kinase mutation‐oriented strategies for therapeutic interference. Besides phosphotransferase activity, protein abundance, and intermolecular interactions, particular patient‐mutations promote pathological ki...

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Detalles Bibliográficos
Autores principales:	Enzler, Florian, Tschaikner, Philipp, Schneider, Rainer, Stefan, Eduard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318358/ https://www.ncbi.nlm.nih.gov/pubmed/32027084 http://dx.doi.org/10.1002/iub.2241

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