RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases

The RNA binding protein (RBP) RBM45 forms nuclear and cytoplasmic inclusions in neurons and glia in amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP), and Alzheimer’s disease (AD). The normal functions of RBM45 are poorly understood, as are t...

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Detalles Bibliográficos
Autores principales: Collins, Mahlon, Li, Yang, Bowser, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318465/
https://www.ncbi.nlm.nih.gov/pubmed/32586379
http://dx.doi.org/10.1186/s40478-020-00965-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318465/
https://www.ncbi.nlm.nih.gov/pubmed/32586379
http://dx.doi.org/10.1186/s40478-020-00965-y

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