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Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

BACKGROUND: Small cell lung cancer (SCLC) is an aggressive neuroendocrine lung cancer. SCLC progression and treatment resistance involve epigenetic processes. However, links between SCLC DNA methylation and drug response remain unclear. We performed an epigenome-wide study of 66 human SCLC cell line...

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Detalles Bibliográficos
Autores principales:	Krushkal, Julia, Silvers, Thomas, Reinhold, William C., Sonkin, Dmitriy, Vural, Suleyman, Connelly, John, Varma, Sudhir, Meltzer, Paul S., Kunkel, Mark, Rapisarda, Annamaria, Evans, David, Pommier, Yves, Teicher, Beverly A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318526/ https://www.ncbi.nlm.nih.gov/pubmed/32586373 http://dx.doi.org/10.1186/s13148-020-00876-8

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