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Lung delivery of MSCs expressing anti-cancer protein TRAIL visualised with (89)Zr-oxine PET-CT
BACKGROUND: MSCTRAIL is a cell-based therapy consisting of human allogeneic umbilical cord-derived MSCs genetically modified to express the anti-cancer protein TRAIL. Though cell-based therapies are typically designed with a target tissue in mind, delivery is rarely assessed due to a lack of transla...
Autores principales: | Patrick, P. Stephen, Kolluri, Krishna K., Zaw Thin, May, Edwards, Adam, Sage, Elizabeth K., Sanderson, Tom, Weil, Benjamin D., Dickson, John C., Lythgoe, Mark F., Lowdell, Mark, Janes, Sam M., Kalber, Tammy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318529/ https://www.ncbi.nlm.nih.gov/pubmed/32586403 http://dx.doi.org/10.1186/s13287-020-01770-z |
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