A case report of primary upper urinary tract signet-ring cell carcinoma and literature review

BACKGROUND: Upper tract urothelial carcinoma with pure non-urothelial histology is an exception but variants are present in ~ 25% of cases. Primary upper urinary tract signet -ring cell carcinoma is extremely rare. CASE PRESENTATION: We report the case of a 65-year-old male diagnosed primary upper u...

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Detalles Bibliográficos
Autores principales: Ye, Zhaohua, Mi, Qiwu, Luo, Daosheng, Li, Zhixiong, Luo, Jiexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318531/
https://www.ncbi.nlm.nih.gov/pubmed/32590974
http://dx.doi.org/10.1186/s12894-020-00645-y
Descripción
Sumario:BACKGROUND: Upper tract urothelial carcinoma with pure non-urothelial histology is an exception but variants are present in ~ 25% of cases. Primary upper urinary tract signet -ring cell carcinoma is extremely rare. CASE PRESENTATION: We report the case of a 65-year-old male diagnosed primary upper urinary tract signet-ring cell carcinoma while underwent percutaneous nephrolithotomy. Radical nephroureterectomy and adjuvant chemotherapy were performed sequentially. The patient is now recovering well with a regular follow-up for more than 1 year. CONCLUSIONS: The upper urinary tract malignancy often appears as a high grade, high stage tumor and has a uniformly poor prognosis, but a timely multimodal management can bring a good outcome.

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