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EPR Distance Measurements on Long Non‐coding RNAs Empowered by Genetic Alphabet Expansion Transcription

We present herein a novel nitroxide spin label‐containing RNA triphosphate TPT3(NO) and its application for site‐specific spin‐labeling of RNA through in vitro transcription using an expanded genetic alphabet. Our strategy allows the facile preparation of spin‐labeled RNAs with sizes ranging from sh...

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Detalles Bibliográficos
Autores principales: Domnick, Christof, Eggert, Frank, Wuebben, Christine, Bornewasser, Lisa, Hagelueken, Gregor, Schiemann, Olav, Kath‐Schorr, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318606/
https://www.ncbi.nlm.nih.gov/pubmed/31981397
http://dx.doi.org/10.1002/anie.201916447

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