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Therapeutic and prophylactic deletion of IL‐4Ra‐signaling ameliorates established ovalbumin induced allergic asthma
BACKGROUND: Allergic asthma is a chronic inflammatory airway disease driven predominantly by a T(H)2 immune response to environmental allergens. IL‐4Rα‐signaling is essential for driving T(H)2‐type immunity to allergens. Anti‐T(H)2 therapies have the potential to effectively reduce airway obstructio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318634/ https://www.ncbi.nlm.nih.gov/pubmed/31782803 http://dx.doi.org/10.1111/all.14137 |