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Therapeutic and prophylactic deletion of IL‐4Ra‐signaling ameliorates established ovalbumin induced allergic asthma

BACKGROUND: Allergic asthma is a chronic inflammatory airway disease driven predominantly by a T(H)2 immune response to environmental allergens. IL‐4Rα‐signaling is essential for driving T(H)2‐type immunity to allergens. Anti‐T(H)2 therapies have the potential to effectively reduce airway obstructio...

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Detalles Bibliográficos
Autores principales:	Khumalo, Jermaine, Kirstein, Frank, Scibiorek, Martyna, Hadebe, Sabelo, Brombacher, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318634/ https://www.ncbi.nlm.nih.gov/pubmed/31782803 http://dx.doi.org/10.1111/all.14137

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