The whole‐cell Ca(2+) release‐activated Ca(2+) current, I (CRAC), is regulated by the mitochondrial Ca(2+) uniporter channel and is independent of extracellular and cytosolic Na(+)

KEY POINTS: Ca(2+) entry through Ca(2+) release‐activated Ca(2+) channels activates numerous cellular responses. Under physiological conditions of weak intracellular Ca(2+) buffering, mitochondrial Ca(2+) uptake regulates CRAC channel activity. Knockdown of the mitochondrial Ca(2+) uniporter channel...

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Detalles Bibliográficos
Autores principales: Samanta, Krishna, Bakowski, Daniel, Amin, Nader, Parekh, Anant B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Symposium Related Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318671/
https://www.ncbi.nlm.nih.gov/pubmed/30582626
http://dx.doi.org/10.1113/JP276551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318671/
https://www.ncbi.nlm.nih.gov/pubmed/30582626
http://dx.doi.org/10.1113/JP276551

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