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Repurposing Antiviral Drugs for Orthogonal RNA‐Catalyzed Labeling of RNA

In vitro selected ribozymes are promising tools for site‐specific labeling of RNA. Previously known nucleic acid catalysts attached fluorescently labeled adenosine or guanosine derivatives through 2′,5′‐branched phosphodiester bonds to the RNA of interest. Herein, we report new ribozymes that use or...

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Detalles Bibliográficos
Autores principales: Ghaem Maghami, Mohammad, Dey, Surjendu, Lenz, Ann‐Kathrin, Höbartner, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318677/
https://www.ncbi.nlm.nih.gov/pubmed/32162405
http://dx.doi.org/10.1002/anie.202001300