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Application of CRISPR/Cas9 to human-induced pluripotent stem cells: from gene editing to drug discovery
Human-induced pluripotent stem cells (hiPSCs) and CRISPR/Cas9 gene editing system represent two instruments of basic and translational research, which both allow to acquire deep insight about the molecular bases of many diseases but also to develop pharmacological research. This review is focused to...
Autores principales: | De Masi, Claudia, Spitalieri, Paola, Murdocca, Michela, Novelli, Giuseppe, Sangiuolo, Federica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318728/ https://www.ncbi.nlm.nih.gov/pubmed/32591003 http://dx.doi.org/10.1186/s40246-020-00276-2 |
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