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Mitochondria transfer enhances proliferation, migration, and osteogenic differentiation of bone marrow mesenchymal stem cell and promotes bone defect healing

BACKGROUND: Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is considered a promising therapeutic approach for bone defect repair. However, during the transplantation procedure, the functions and viability of BMSCs may be impaired due to extended durations of in vitro culture, aging...

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Detalles Bibliográficos
Autores principales: Guo, Yusi, Chi, Xiaopei, Wang, Yifan, Heng, Boon Chin, Wei, Yan, Zhang, Xuehui, Zhao, Han, Yin, Ying, Deng, Xuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318752/
https://www.ncbi.nlm.nih.gov/pubmed/32586355
http://dx.doi.org/10.1186/s13287-020-01704-9