Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage

Primary gastric lymphoma is rare, representing 5% of all primary gastric neoplasms. The presenting complaints of gastric mucosa-associated lymphoid tissue (MALT) lymphoma are usually nonspecific. However, life-threatening gastrointestinal bleeding from the stomach is unusual and sparsely reported. W...

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Autores principales: Harne, Prateek S., Mukherjee, Samiran, Achufusi, Ted, Lowe, Dhruv, Manocha, Divey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318806/
https://www.ncbi.nlm.nih.gov/pubmed/32583695
http://dx.doi.org/10.1177/2324709620937166
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author Harne, Prateek S.
Mukherjee, Samiran
Achufusi, Ted
Lowe, Dhruv
Manocha, Divey
author_facet Harne, Prateek S.
Mukherjee, Samiran
Achufusi, Ted
Lowe, Dhruv
Manocha, Divey
author_sort Harne, Prateek S.
collection PubMed
description Primary gastric lymphoma is rare, representing 5% of all primary gastric neoplasms. The presenting complaints of gastric mucosa-associated lymphoid tissue (MALT) lymphoma are usually nonspecific. However, life-threatening gastrointestinal bleeding from the stomach is unusual and sparsely reported. While studies reveal an indolent course, we present a case that presented with massive and recurrent hematemesis leading to hypovolemic shock secondary to endoscopically confirmed MALT lymphoma, which was treated with radiotherapy to achieve remission. She had no autoimmune diseases and tested negative for Helicobacter pylori. Our case emphasizes the importance of early diagnosis and timely intensive radiotherapy of a localized but aggressive gastric MALT lymphoma.
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spelling pubmed-73188062020-07-06 Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage Harne, Prateek S. Mukherjee, Samiran Achufusi, Ted Lowe, Dhruv Manocha, Divey J Investig Med High Impact Case Rep Case Report Primary gastric lymphoma is rare, representing 5% of all primary gastric neoplasms. The presenting complaints of gastric mucosa-associated lymphoid tissue (MALT) lymphoma are usually nonspecific. However, life-threatening gastrointestinal bleeding from the stomach is unusual and sparsely reported. While studies reveal an indolent course, we present a case that presented with massive and recurrent hematemesis leading to hypovolemic shock secondary to endoscopically confirmed MALT lymphoma, which was treated with radiotherapy to achieve remission. She had no autoimmune diseases and tested negative for Helicobacter pylori. Our case emphasizes the importance of early diagnosis and timely intensive radiotherapy of a localized but aggressive gastric MALT lymphoma. SAGE Publications 2020-06-25 /pmc/articles/PMC7318806/ /pubmed/32583695 http://dx.doi.org/10.1177/2324709620937166 Text en © 2020 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Harne, Prateek S.
Mukherjee, Samiran
Achufusi, Ted
Lowe, Dhruv
Manocha, Divey
Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage
title Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage
title_full Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage
title_fullStr Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage
title_full_unstemmed Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage
title_short Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage
title_sort helicobacter pylori–negative malt lymphoma presenting as a massive recurrent gastrointestinal hemorrhage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318806/
https://www.ncbi.nlm.nih.gov/pubmed/32583695
http://dx.doi.org/10.1177/2324709620937166
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