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Ribotype Classification of Clostridioides difficile Isolates Is Not Predictive of the Amino Acid Sequence Diversity of the Toxin Virulence Factors TcdA and TcdB

Clostridioides (Clostridium) difficile is the most commonly recognized cause of infectious diarrhea in healthcare settings. Currently there is no vaccine to prevent initial or recurrent C. difficile infection (CDI). Two large clostridial toxins, TcdA and TcdB, are the primary virulence factors for C...

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Detalles Bibliográficos
Autores principales: Li, Zhenghui, Lee, Kwok, Rajyaguru, Urvi, Jones, C. Hal, Janezic, Sandra, Rupnik, Maja, Anderson, Annaliesa S., Liberator, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318873/
https://www.ncbi.nlm.nih.gov/pubmed/32636819
http://dx.doi.org/10.3389/fmicb.2020.01310