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Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain
Despite growing evidence suggesting that spinal microglia play an important role in the molecular mechanism underlying experimental neuropathic pain (NP) in male rodents, evidence regarding the sex-dependent role of these microglia in NP is insufficient. In this study, we evaluated the effects of mi...
Autores principales: | Saika, Fumihiro, Matsuzaki, Shinsuke, Kobayashi, Daichi, Ideguchi, Yuya, Nakamura, Tomoe Y., Kishioka, Shiroh, Kiguchi, Norikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318895/ https://www.ncbi.nlm.nih.gov/pubmed/32636748 http://dx.doi.org/10.3389/fphar.2020.00925 |
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