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Identification of pathognomonic purine synthesis biomarkers by metabolomic profiling of adolescents with obesity and type 2 diabetes
The incidence of type 2 diabetes is increasing more rapidly in adolescents than in any other age group. We identified and compared metabolite signatures in obese children with type 2 diabetes (T2D), obese children without diabetes (OB), and healthy, age- and gender-matched normal weight controls (NW...
Autores principales: | Concepcion, Jennifer, Chen, Katherine, Saito, Rintaro, Gangoiti, Jon, Mendez, Eric, Nikita, Maria Eleni, Barshop, Bruce A., Natarajan, Loki, Sharma, Kumar, Kim, Jane J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319336/ https://www.ncbi.nlm.nih.gov/pubmed/32589682 http://dx.doi.org/10.1371/journal.pone.0234970 |
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