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Preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: Implications from coverage validation survey in Ethiopia, 2019

BACKGROUND: Soil-transmitted helminth (STH) infections remain the most common neglected tropical diseases among children living mainly in low-resource settings. Preventive chemotherapy (PC) has been implemented as one of the main public health interventions to control and eliminate STH infections. A...

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Autores principales: Asfaw, Mekuria Asnakew, Zerdo, Zerihun, Churko, Chuchu, Seife, Fikre, Yihune, Manaye, Chisha, Yilma, Teshome, Abinet, Getachew, Birhanu, Negussu, Nebiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319348/
https://www.ncbi.nlm.nih.gov/pubmed/32589660
http://dx.doi.org/10.1371/journal.pone.0235281
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author Asfaw, Mekuria Asnakew
Zerdo, Zerihun
Churko, Chuchu
Seife, Fikre
Yihune, Manaye
Chisha, Yilma
Teshome, Abinet
Getachew, Birhanu
Negussu, Nebiyu
author_facet Asfaw, Mekuria Asnakew
Zerdo, Zerihun
Churko, Chuchu
Seife, Fikre
Yihune, Manaye
Chisha, Yilma
Teshome, Abinet
Getachew, Birhanu
Negussu, Nebiyu
author_sort Asfaw, Mekuria Asnakew
collection PubMed
description BACKGROUND: Soil-transmitted helminth (STH) infections remain the most common neglected tropical diseases among children living mainly in low-resource settings. Preventive chemotherapy (PC) has been implemented as one of the main public health interventions to control and eliminate STH infections. Although data on routine coverage of PC against STH are available at different level of the health system; these data are unreliable as they are subject to errors and manipulation and evidence is lacking on validated treatment coverage. Thus, this study aimed to determine anthelminthic coverage among school age children (SAC) to inform decision made in PC program implementation. METHODS: We conducted a community-based cross-sectional coverage survey in ten districts of Ethiopia; in April 2019. Sample size was computed automatically using Coverage Survey Builder (CSB) tool in Microsoft excel. Thirty segments were randomly selected per each selected districts. Collected data were cleaned and analysed using SPSS software (IBM, version 25). PRINCIPAL FINDINGS: In all, 8154 SAC participated in the study. The overall anthelminthic coverage was found to be 71% (95%confidence interval (CI) = 70–71.9%). The reported coverage was lower than the surveyed coverage only in Guagusa district. The PC coverage among males (71.9%) was slightly higher than females’ coverage (70%); and the coverage in the age group between10 and 14 years (77%) was higher compared with the age group between 5 and 9 years (64.3%). In addition, the PC coverage in school attending children (81.1%) was much higher than coverage in non-enrolled children (28.3%). Moreover, the most frequently mentioned reasons for not swallowing drugs were drug not given (24.75%) and not attending school (19.75%). CONCUSSION: This study showed that only five out of ten districts met the target threshold (minimum 75%) for effective coverage. Hence, implementations of preventive chemotherapy should be improved in those districts with low coverage data.
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spelling pubmed-73193482020-06-30 Preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: Implications from coverage validation survey in Ethiopia, 2019 Asfaw, Mekuria Asnakew Zerdo, Zerihun Churko, Chuchu Seife, Fikre Yihune, Manaye Chisha, Yilma Teshome, Abinet Getachew, Birhanu Negussu, Nebiyu PLoS One Research Article BACKGROUND: Soil-transmitted helminth (STH) infections remain the most common neglected tropical diseases among children living mainly in low-resource settings. Preventive chemotherapy (PC) has been implemented as one of the main public health interventions to control and eliminate STH infections. Although data on routine coverage of PC against STH are available at different level of the health system; these data are unreliable as they are subject to errors and manipulation and evidence is lacking on validated treatment coverage. Thus, this study aimed to determine anthelminthic coverage among school age children (SAC) to inform decision made in PC program implementation. METHODS: We conducted a community-based cross-sectional coverage survey in ten districts of Ethiopia; in April 2019. Sample size was computed automatically using Coverage Survey Builder (CSB) tool in Microsoft excel. Thirty segments were randomly selected per each selected districts. Collected data were cleaned and analysed using SPSS software (IBM, version 25). PRINCIPAL FINDINGS: In all, 8154 SAC participated in the study. The overall anthelminthic coverage was found to be 71% (95%confidence interval (CI) = 70–71.9%). The reported coverage was lower than the surveyed coverage only in Guagusa district. The PC coverage among males (71.9%) was slightly higher than females’ coverage (70%); and the coverage in the age group between10 and 14 years (77%) was higher compared with the age group between 5 and 9 years (64.3%). In addition, the PC coverage in school attending children (81.1%) was much higher than coverage in non-enrolled children (28.3%). Moreover, the most frequently mentioned reasons for not swallowing drugs were drug not given (24.75%) and not attending school (19.75%). CONCUSSION: This study showed that only five out of ten districts met the target threshold (minimum 75%) for effective coverage. Hence, implementations of preventive chemotherapy should be improved in those districts with low coverage data. Public Library of Science 2020-06-26 /pmc/articles/PMC7319348/ /pubmed/32589660 http://dx.doi.org/10.1371/journal.pone.0235281 Text en © 2020 Asfaw et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Asfaw, Mekuria Asnakew
Zerdo, Zerihun
Churko, Chuchu
Seife, Fikre
Yihune, Manaye
Chisha, Yilma
Teshome, Abinet
Getachew, Birhanu
Negussu, Nebiyu
Preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: Implications from coverage validation survey in Ethiopia, 2019
title Preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: Implications from coverage validation survey in Ethiopia, 2019
title_full Preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: Implications from coverage validation survey in Ethiopia, 2019
title_fullStr Preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: Implications from coverage validation survey in Ethiopia, 2019
title_full_unstemmed Preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: Implications from coverage validation survey in Ethiopia, 2019
title_short Preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: Implications from coverage validation survey in Ethiopia, 2019
title_sort preventive chemotherapy coverage against soil-transmitted helminth infection among school age children: implications from coverage validation survey in ethiopia, 2019
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319348/
https://www.ncbi.nlm.nih.gov/pubmed/32589660
http://dx.doi.org/10.1371/journal.pone.0235281
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