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Factors associated with tuberculosis in persons deprived of liberty in Espírito Santo

OBJECTIVES: To calculate the rate of tuberculosis cases per prison unit in Espírito Santo; present the individual, clinical, and institutional characteristics of the cases in persons deprived of liberty (PPL); and analyze the association between these characteristics and treatment outcome in this po...

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Autores principales: Macedo, Laylla Ribeiro, Maciel, Ethel Leonor Noia, Struchiner, Claudio Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Saúde Pública da Universidade de São Paulo 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319498/
https://www.ncbi.nlm.nih.gov/pubmed/32638882
http://dx.doi.org/10.11606/s1518-8787.2020054001818
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author Macedo, Laylla Ribeiro
Maciel, Ethel Leonor Noia
Struchiner, Claudio Jose
author_facet Macedo, Laylla Ribeiro
Maciel, Ethel Leonor Noia
Struchiner, Claudio Jose
author_sort Macedo, Laylla Ribeiro
collection PubMed
description OBJECTIVES: To calculate the rate of tuberculosis cases per prison unit in Espírito Santo; present the individual, clinical, and institutional characteristics of the cases in persons deprived of liberty (PPL); and analyze the association between these characteristics and treatment outcome in this population. METHODS: The study included cases of tuberculosis in the PPL of Espírito Santo from 2014 to 2016. Rate calculation, descriptive analysis and hierarchical logistic regression were performed considering the individual, clinical and institutional levels. RESULTS: The rate of diagnosed cases per prison unit in the state ranged from 0 to 17.3 cases per 1,000 inmates. Of all reported cases, 218 (72.6%) healed, 21 (7.0%) dropped out, 1 (0.3%) died of tuberculosis, 2 (0.7%) died from other causes, 56 (18.7%) transferred the treatment site and 2 (0.7%) developed drug-resistant tuberculosis. The adjusted analysis showed that supervised treatment ensures success (CR = 0.29; 95%CI 0.01–0.76). CONCLUSIONS: The study highlighted the importance of knowing the TB treatment outcome in the PPL to implement measures to reduce failure, and the contribution of supervised treatment in this process.
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spelling pubmed-73194982020-07-06 Factors associated with tuberculosis in persons deprived of liberty in Espírito Santo Macedo, Laylla Ribeiro Maciel, Ethel Leonor Noia Struchiner, Claudio Jose Rev Saude Publica Original Article OBJECTIVES: To calculate the rate of tuberculosis cases per prison unit in Espírito Santo; present the individual, clinical, and institutional characteristics of the cases in persons deprived of liberty (PPL); and analyze the association between these characteristics and treatment outcome in this population. METHODS: The study included cases of tuberculosis in the PPL of Espírito Santo from 2014 to 2016. Rate calculation, descriptive analysis and hierarchical logistic regression were performed considering the individual, clinical and institutional levels. RESULTS: The rate of diagnosed cases per prison unit in the state ranged from 0 to 17.3 cases per 1,000 inmates. Of all reported cases, 218 (72.6%) healed, 21 (7.0%) dropped out, 1 (0.3%) died of tuberculosis, 2 (0.7%) died from other causes, 56 (18.7%) transferred the treatment site and 2 (0.7%) developed drug-resistant tuberculosis. The adjusted analysis showed that supervised treatment ensures success (CR = 0.29; 95%CI 0.01–0.76). CONCLUSIONS: The study highlighted the importance of knowing the TB treatment outcome in the PPL to implement measures to reduce failure, and the contribution of supervised treatment in this process. Faculdade de Saúde Pública da Universidade de São Paulo 2020-06-26 /pmc/articles/PMC7319498/ /pubmed/32638882 http://dx.doi.org/10.11606/s1518-8787.2020054001818 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Macedo, Laylla Ribeiro
Maciel, Ethel Leonor Noia
Struchiner, Claudio Jose
Factors associated with tuberculosis in persons deprived of liberty in Espírito Santo
title Factors associated with tuberculosis in persons deprived of liberty in Espírito Santo
title_full Factors associated with tuberculosis in persons deprived of liberty in Espírito Santo
title_fullStr Factors associated with tuberculosis in persons deprived of liberty in Espírito Santo
title_full_unstemmed Factors associated with tuberculosis in persons deprived of liberty in Espírito Santo
title_short Factors associated with tuberculosis in persons deprived of liberty in Espírito Santo
title_sort factors associated with tuberculosis in persons deprived of liberty in espírito santo
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319498/
https://www.ncbi.nlm.nih.gov/pubmed/32638882
http://dx.doi.org/10.11606/s1518-8787.2020054001818
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