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NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of MHC antigen presentation by concurrent motif deconvolution and integration of MS MHC eluted ligand data

Major histocompatibility complex (MHC) molecules are expressed on the cell surface, where they present peptides to T cells, which gives them a key role in the development of T-cell immune responses. MHC molecules come in two main variants: MHC Class I (MHC-I) and MHC Class II (MHC-II). MHC-I predomi...

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Detalles Bibliográficos
Autores principales: Reynisson, Birkir, Alvarez, Bruno, Paul, Sinu, Peters, Bjoern, Nielsen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319546/
https://www.ncbi.nlm.nih.gov/pubmed/32406916
http://dx.doi.org/10.1093/nar/gkaa379