3D-GNOME 2.0: a three-dimensional genome modeling engine for predicting structural variation-driven alterations of chromatin spatial structure in the human genome

Structural variants (SVs) that alter DNA sequence emerge as a driving force involved in the reorganisation of DNA spatial folding, thus affecting gene transcription. In this work, we describe an improved version of our integrated web service for structural modeling of three-dimensional genome (3D-GN...

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Detalles Bibliográficos
Autores principales: Wlasnowolski, Michal, Sadowski, Michal, Czarnota, Tymon, Jodkowska, Karolina, Szalaj, Przemyslaw, Tang, Zhonghui, Ruan, Yijun, Plewczynski, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Web Server Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319547/
https://www.ncbi.nlm.nih.gov/pubmed/32442297
http://dx.doi.org/10.1093/nar/gkaa388

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