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Oviz-Bio: a web-based platform for interactive cancer genomics data visualization

Genetics data visualization plays an important role in the sharing of knowledge from cancer genome research. Many types of visualization are widely used, most of which are static and require sufficient coding experience to create. Here, we present Oviz-Bio, a web-based platform that provides interac...

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Detalles Bibliográficos
Autores principales: Jia, Wenlong, Li, Hechen, Li, Shiying, Chen, Lingxi, Li, Shuai Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319551/
https://www.ncbi.nlm.nih.gov/pubmed/32392343
http://dx.doi.org/10.1093/nar/gkaa371
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author Jia, Wenlong
Li, Hechen
Li, Shiying
Chen, Lingxi
Li, Shuai Cheng
author_facet Jia, Wenlong
Li, Hechen
Li, Shiying
Chen, Lingxi
Li, Shuai Cheng
author_sort Jia, Wenlong
collection PubMed
description Genetics data visualization plays an important role in the sharing of knowledge from cancer genome research. Many types of visualization are widely used, most of which are static and require sufficient coding experience to create. Here, we present Oviz-Bio, a web-based platform that provides interactive and real-time visualizations of cancer genomics data. Researchers can interactively explore visual outputs and export high-quality diagrams. Oviz-Bio supports a diverse range of visualizations on common cancer mutation types, including annotation and signatures of small scale mutations, haplotype view and focal clusters of copy number variations, split-reads alignment and heatmap view of structural variations, transcript junction of fusion genes and genomic hotspot of oncovirus integrations. Furthermore, Oviz-Bio allows landscape view to investigate multi-layered data in samples cohort. All Oviz-Bio visual applications are freely available at https://bio.oviz.org/.
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spelling pubmed-73195512020-07-13 Oviz-Bio: a web-based platform for interactive cancer genomics data visualization Jia, Wenlong Li, Hechen Li, Shiying Chen, Lingxi Li, Shuai Cheng Nucleic Acids Res Web Server Issue Genetics data visualization plays an important role in the sharing of knowledge from cancer genome research. Many types of visualization are widely used, most of which are static and require sufficient coding experience to create. Here, we present Oviz-Bio, a web-based platform that provides interactive and real-time visualizations of cancer genomics data. Researchers can interactively explore visual outputs and export high-quality diagrams. Oviz-Bio supports a diverse range of visualizations on common cancer mutation types, including annotation and signatures of small scale mutations, haplotype view and focal clusters of copy number variations, split-reads alignment and heatmap view of structural variations, transcript junction of fusion genes and genomic hotspot of oncovirus integrations. Furthermore, Oviz-Bio allows landscape view to investigate multi-layered data in samples cohort. All Oviz-Bio visual applications are freely available at https://bio.oviz.org/. Oxford University Press 2020-07-02 2020-05-11 /pmc/articles/PMC7319551/ /pubmed/32392343 http://dx.doi.org/10.1093/nar/gkaa371 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Web Server Issue
Jia, Wenlong
Li, Hechen
Li, Shiying
Chen, Lingxi
Li, Shuai Cheng
Oviz-Bio: a web-based platform for interactive cancer genomics data visualization
title Oviz-Bio: a web-based platform for interactive cancer genomics data visualization
title_full Oviz-Bio: a web-based platform for interactive cancer genomics data visualization
title_fullStr Oviz-Bio: a web-based platform for interactive cancer genomics data visualization
title_full_unstemmed Oviz-Bio: a web-based platform for interactive cancer genomics data visualization
title_short Oviz-Bio: a web-based platform for interactive cancer genomics data visualization
title_sort oviz-bio: a web-based platform for interactive cancer genomics data visualization
topic Web Server Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319551/
https://www.ncbi.nlm.nih.gov/pubmed/32392343
http://dx.doi.org/10.1093/nar/gkaa371
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