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Oviz-Bio: a web-based platform for interactive cancer genomics data visualization
Genetics data visualization plays an important role in the sharing of knowledge from cancer genome research. Many types of visualization are widely used, most of which are static and require sufficient coding experience to create. Here, we present Oviz-Bio, a web-based platform that provides interac...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319551/ https://www.ncbi.nlm.nih.gov/pubmed/32392343 http://dx.doi.org/10.1093/nar/gkaa371 |
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author | Jia, Wenlong Li, Hechen Li, Shiying Chen, Lingxi Li, Shuai Cheng |
author_facet | Jia, Wenlong Li, Hechen Li, Shiying Chen, Lingxi Li, Shuai Cheng |
author_sort | Jia, Wenlong |
collection | PubMed |
description | Genetics data visualization plays an important role in the sharing of knowledge from cancer genome research. Many types of visualization are widely used, most of which are static and require sufficient coding experience to create. Here, we present Oviz-Bio, a web-based platform that provides interactive and real-time visualizations of cancer genomics data. Researchers can interactively explore visual outputs and export high-quality diagrams. Oviz-Bio supports a diverse range of visualizations on common cancer mutation types, including annotation and signatures of small scale mutations, haplotype view and focal clusters of copy number variations, split-reads alignment and heatmap view of structural variations, transcript junction of fusion genes and genomic hotspot of oncovirus integrations. Furthermore, Oviz-Bio allows landscape view to investigate multi-layered data in samples cohort. All Oviz-Bio visual applications are freely available at https://bio.oviz.org/. |
format | Online Article Text |
id | pubmed-7319551 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-73195512020-07-13 Oviz-Bio: a web-based platform for interactive cancer genomics data visualization Jia, Wenlong Li, Hechen Li, Shiying Chen, Lingxi Li, Shuai Cheng Nucleic Acids Res Web Server Issue Genetics data visualization plays an important role in the sharing of knowledge from cancer genome research. Many types of visualization are widely used, most of which are static and require sufficient coding experience to create. Here, we present Oviz-Bio, a web-based platform that provides interactive and real-time visualizations of cancer genomics data. Researchers can interactively explore visual outputs and export high-quality diagrams. Oviz-Bio supports a diverse range of visualizations on common cancer mutation types, including annotation and signatures of small scale mutations, haplotype view and focal clusters of copy number variations, split-reads alignment and heatmap view of structural variations, transcript junction of fusion genes and genomic hotspot of oncovirus integrations. Furthermore, Oviz-Bio allows landscape view to investigate multi-layered data in samples cohort. All Oviz-Bio visual applications are freely available at https://bio.oviz.org/. Oxford University Press 2020-07-02 2020-05-11 /pmc/articles/PMC7319551/ /pubmed/32392343 http://dx.doi.org/10.1093/nar/gkaa371 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Web Server Issue Jia, Wenlong Li, Hechen Li, Shiying Chen, Lingxi Li, Shuai Cheng Oviz-Bio: a web-based platform for interactive cancer genomics data visualization |
title | Oviz-Bio: a web-based platform for interactive cancer genomics data visualization |
title_full | Oviz-Bio: a web-based platform for interactive cancer genomics data visualization |
title_fullStr | Oviz-Bio: a web-based platform for interactive cancer genomics data visualization |
title_full_unstemmed | Oviz-Bio: a web-based platform for interactive cancer genomics data visualization |
title_short | Oviz-Bio: a web-based platform for interactive cancer genomics data visualization |
title_sort | oviz-bio: a web-based platform for interactive cancer genomics data visualization |
topic | Web Server Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319551/ https://www.ncbi.nlm.nih.gov/pubmed/32392343 http://dx.doi.org/10.1093/nar/gkaa371 |
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