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Safety and immunogenicity of novel 5T4 viral vectored vaccination regimens in early stage prostate cancer: a phase I clinical trial
BACKGROUND: Prostate cancer (PCa) has been under investigation as a target for antigen-specific immunotherapies in metastatic disease settings for the last two decades leading to a licensure of the first therapeutic cancer vaccine, Sipuleucel-T, in 2010. However, neither Sipuleucel-T nor other exper...
Autores principales: | Cappuccini, Federica, Bryant, Richard, Pollock, Emily, Carter, Lucy, Verrill, Clare, Hollidge, Julianne, Poulton, Ian, Baker, Megan, Mitton, Celia, Baines, Andrea, Meier, Armin, Schmidt, Guenter, Harrop, Richard, Protheroe, Andrew, MacPherson, Ruth, Kennish, Steven, Morgan, Susan, Vigano, Selena, Romero, Pedro J, Evans, Thomas, Catto, James, Hamdy, Freddie, Hill, Adrian V S, Redchenko, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319775/ https://www.ncbi.nlm.nih.gov/pubmed/32591433 http://dx.doi.org/10.1136/jitc-2020-000928 |
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