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IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma

BACKGROUND: We have previously discovered a relationship between the low expression of protein tyrosine phosphatase, receptor type O (PTPRO) in tumor-infiltrating T cells and immunosuppression. The aim of the present study was to investigate the relationship between decreased PTPRO and increased pro...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjie, Liu, Yang, Yan, Zhongyi, Yang, Hui, Sun, Wei, Yao, Yongliang, Chen, Yun, Jiang, Runqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319788/
https://www.ncbi.nlm.nih.gov/pubmed/32581055
http://dx.doi.org/10.1136/jitc-2019-000285

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