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Cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report

BACKGROUND: Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone, with iodine deficiency remains the foremost cause. It is more common in women with increasing incidence in the elderly. The manifestations of hypothyroidism results from the hypometabolism in the...

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Autores principales: Maddali, Vikas Reddy, Miryala, Srikar, Bellamkonda, Yagna Sreekanth, Nagula, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319808/
https://www.ncbi.nlm.nih.gov/pubmed/32617463
http://dx.doi.org/10.1093/ehjcr/ytaa071
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author Maddali, Vikas Reddy
Miryala, Srikar
Bellamkonda, Yagna Sreekanth
Nagula, Praveen
author_facet Maddali, Vikas Reddy
Miryala, Srikar
Bellamkonda, Yagna Sreekanth
Nagula, Praveen
author_sort Maddali, Vikas Reddy
collection PubMed
description BACKGROUND: Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone, with iodine deficiency remains the foremost cause. It is more common in women with increasing incidence in the elderly. The manifestations of hypothyroidism results from the hypometabolism in the body at cellular level and affects all organs. Although there can be an incidental diagnosis of the disorder, the presentation with cardiac signs and symptoms is rare. We report a case of primary hypothyroidism with dysmorphic features manifesting as massive pericardial effusion with cardiac tamponade at presentation. CASE SUMMARY: A female aged 20 years presented with lethargy, constipation, and dyspnoea of 6 months duration. On examination, she was short-statured and had dysmorphic features with hypotension, raised jugular venous pressure (JVP), muffled heart sounds, and thyroid stimulating hormone >100 uIU/mL. Chest X-ray showed cardiomegaly and 2DEcho confirmed cardiac tamponade for which emergency pericardiocentesis was done. DISCUSSION: Cardiovascular manifestations in hypothyroidism are dyspnoea and decreased exercise tolerance. Bradycardia, diastolic hypertension, cardiomegaly, and non-pitting or pitting peripheral oedema may be seen on physical examination. Mild pericardial effusion is common and generally asymptomatic. Massive pericardial effusion being manifested at presentation primarily as a sign of hypothyroidism is rare. A few cases have been mentioned in the literature in India and western population. Rarely, hypothyroidism presents with massive pericardial effusion resulting in cardiac tamponade as in our case.
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spelling pubmed-73198082020-07-01 Cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report Maddali, Vikas Reddy Miryala, Srikar Bellamkonda, Yagna Sreekanth Nagula, Praveen Eur Heart J Case Rep Case Reports BACKGROUND: Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone, with iodine deficiency remains the foremost cause. It is more common in women with increasing incidence in the elderly. The manifestations of hypothyroidism results from the hypometabolism in the body at cellular level and affects all organs. Although there can be an incidental diagnosis of the disorder, the presentation with cardiac signs and symptoms is rare. We report a case of primary hypothyroidism with dysmorphic features manifesting as massive pericardial effusion with cardiac tamponade at presentation. CASE SUMMARY: A female aged 20 years presented with lethargy, constipation, and dyspnoea of 6 months duration. On examination, she was short-statured and had dysmorphic features with hypotension, raised jugular venous pressure (JVP), muffled heart sounds, and thyroid stimulating hormone >100 uIU/mL. Chest X-ray showed cardiomegaly and 2DEcho confirmed cardiac tamponade for which emergency pericardiocentesis was done. DISCUSSION: Cardiovascular manifestations in hypothyroidism are dyspnoea and decreased exercise tolerance. Bradycardia, diastolic hypertension, cardiomegaly, and non-pitting or pitting peripheral oedema may be seen on physical examination. Mild pericardial effusion is common and generally asymptomatic. Massive pericardial effusion being manifested at presentation primarily as a sign of hypothyroidism is rare. A few cases have been mentioned in the literature in India and western population. Rarely, hypothyroidism presents with massive pericardial effusion resulting in cardiac tamponade as in our case. Oxford University Press 2020-05-03 /pmc/articles/PMC7319808/ /pubmed/32617463 http://dx.doi.org/10.1093/ehjcr/ytaa071 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Reports
Maddali, Vikas Reddy
Miryala, Srikar
Bellamkonda, Yagna Sreekanth
Nagula, Praveen
Cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report
title Cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report
title_full Cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report
title_fullStr Cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report
title_full_unstemmed Cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report
title_short Cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report
title_sort cardiac tamponade due to primary hypothyroidism: acute management and approach to prevent recurrence—a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319808/
https://www.ncbi.nlm.nih.gov/pubmed/32617463
http://dx.doi.org/10.1093/ehjcr/ytaa071
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