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Idiopathic endomyocardial fibrosis in a Western European: a case report
BACKGROUND: Endomyocardial fibrosis (EMF) is a rare cause of restrictive cardiomyopathy, mainly found in tropical/subtropical country. Endomyocardial fibrosis causes severe congestive symptoms and may lead to end-stage heart failure. CASE SUMMARY: A French Caucasian 44-year-old man without noticeabl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319822/ https://www.ncbi.nlm.nih.gov/pubmed/32617477 http://dx.doi.org/10.1093/ehjcr/ytaa104 |
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author | Théry, Guillaume Faroux, Laurent Deleuze, Philippe Metz, Damien |
author_facet | Théry, Guillaume Faroux, Laurent Deleuze, Philippe Metz, Damien |
author_sort | Théry, Guillaume |
collection | PubMed |
description | BACKGROUND: Endomyocardial fibrosis (EMF) is a rare cause of restrictive cardiomyopathy, mainly found in tropical/subtropical country. Endomyocardial fibrosis causes severe congestive symptoms and may lead to end-stage heart failure. CASE SUMMARY: A French Caucasian 44-year-old man without noticeable medical history and who had never travelled outside of France was hospitalized for a first episode of acute heart failure revealing an atypical appearance of the left ventricle. Cardiac magnetic resonance (CMR) identified EMF, but investigations did not identify any aetiology (no eosinophilia). Despite optimal management of chronic heart failure, functional class declined rapidly resulting in several hospitalizations for heart failure. The patient finally underwent an elective heart transplantation with good results at 6-month follow-up. DISCUSSION: Endomyocardial fibrosis exact physiopathology remains unclear, although association with eosinophilia has been reported. Diagnosis is challenging and is based on multi-modal imagery with a central role of CMR. There is no consensus on optimal management, medical therapy having poor outcomes and rate of peri-operative complications being high. Heart transplantation should be considered for eligible patients. |
format | Online Article Text |
id | pubmed-7319822 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-73198222020-07-01 Idiopathic endomyocardial fibrosis in a Western European: a case report Théry, Guillaume Faroux, Laurent Deleuze, Philippe Metz, Damien Eur Heart J Case Rep Case Reports BACKGROUND: Endomyocardial fibrosis (EMF) is a rare cause of restrictive cardiomyopathy, mainly found in tropical/subtropical country. Endomyocardial fibrosis causes severe congestive symptoms and may lead to end-stage heart failure. CASE SUMMARY: A French Caucasian 44-year-old man without noticeable medical history and who had never travelled outside of France was hospitalized for a first episode of acute heart failure revealing an atypical appearance of the left ventricle. Cardiac magnetic resonance (CMR) identified EMF, but investigations did not identify any aetiology (no eosinophilia). Despite optimal management of chronic heart failure, functional class declined rapidly resulting in several hospitalizations for heart failure. The patient finally underwent an elective heart transplantation with good results at 6-month follow-up. DISCUSSION: Endomyocardial fibrosis exact physiopathology remains unclear, although association with eosinophilia has been reported. Diagnosis is challenging and is based on multi-modal imagery with a central role of CMR. There is no consensus on optimal management, medical therapy having poor outcomes and rate of peri-operative complications being high. Heart transplantation should be considered for eligible patients. Oxford University Press 2020-06-01 /pmc/articles/PMC7319822/ /pubmed/32617477 http://dx.doi.org/10.1093/ehjcr/ytaa104 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Reports Théry, Guillaume Faroux, Laurent Deleuze, Philippe Metz, Damien Idiopathic endomyocardial fibrosis in a Western European: a case report |
title | Idiopathic endomyocardial fibrosis in a Western European: a case report |
title_full | Idiopathic endomyocardial fibrosis in a Western European: a case report |
title_fullStr | Idiopathic endomyocardial fibrosis in a Western European: a case report |
title_full_unstemmed | Idiopathic endomyocardial fibrosis in a Western European: a case report |
title_short | Idiopathic endomyocardial fibrosis in a Western European: a case report |
title_sort | idiopathic endomyocardial fibrosis in a western european: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319822/ https://www.ncbi.nlm.nih.gov/pubmed/32617477 http://dx.doi.org/10.1093/ehjcr/ytaa104 |
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