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PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics
Using PROteolysis TArgeting Chimeras (PROTACs) to degrade proteins that are important for tumorigenesis has emerged as a potential therapeutic strategy for cancer. PROTACs are heterobifunctional molecules consisting of one ligand for binding to a protein of interest (POI) and another to an E3 ubiqui...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319888/ https://www.ncbi.nlm.nih.gov/pubmed/32475992 http://dx.doi.org/10.1038/s41388-020-1336-y |