Cargando…
Complement genes contribute sex-biased vulnerability in diverse illnesses
Many common illnesses differentially affect men and women for unknown reasons. The autoimmune diseases lupus and Sjögren’s syndrome affect nine times more women than men(1), whereas schizophrenia affects men more frequently and severely(2). All three illnesses have their strongest common genetic ass...
Autores principales: | Kamitaki, Nolan, Sekar, Aswin, Handsaker, Robert E., de Rivera, Heather, Tooley, Katherine, Morris, David L., Taylor, Kimberly E., Whelan, Christopher W., Tombleson, Philip, Loohuis, Loes M. Olde, Boehnke, Michael, Kimberly, Robert P., Kaufman, Kenneth M., Harley, John B., Langefeld, Carl D., Seidman, Christine E., Pato, Michele T., Pato, Carlos N., Ophoff, Roel A., Graham, Robert R., Criswell, Lindsey A., Vyse, Timothy J., McCarroll, Steven A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319891/ https://www.ncbi.nlm.nih.gov/pubmed/32499649 http://dx.doi.org/10.1038/s41586-020-2277-x |
Ejemplares similares
-
Schizophrenia risk from complex variation of complement component 4
por: Sekar, Aswin, et al.
Publicado: (2016) -
Whole-genome analysis of human embryonic stem cells enables rational line selection based on genetic variation
por: Merkle, Florian T., et al.
Publicado: (2022) -
Hidden protein-altering variants influence diverse human phenotypes
por: Hujoel, Margaux L.A., et al.
Publicado: (2023) -
Structural forms of the human amylase locus and their relationships to SNPs, haplotypes, and obesity
por: Usher, Christina L, et al.
Publicado: (2015) -
State-Dependent Functional Dysconnectivity in Youth With Psychosis Spectrum Symptoms
por: Mennigen, Eva, et al.
Publicado: (2020)