Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis

This study mainly focused on the very serious COVID-19 epidemic situation at present and provided a new insight for the treatment and monitor of patients with COVID-19. Through this meta-analysis, we could draw a conclusion that less expression of blood CD4(+) and CD8(+) T cells count might reflect...

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Detalles Bibliográficos
Autores principales: Hu, Daojun, Li, Li, Shi, Wenjie, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319938/
https://www.ncbi.nlm.nih.gov/pubmed/32598880
http://dx.doi.org/10.1016/j.cca.2020.06.040
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author Hu, Daojun
Li, Li
Shi, Wenjie
Zhang, Li
author_facet Hu, Daojun
Li, Li
Shi, Wenjie
Zhang, Li
author_sort Hu, Daojun
collection PubMed
description This study mainly focused on the very serious COVID-19 epidemic situation at present and provided a new insight for the treatment and monitor of patients with COVID-19. Through this meta-analysis, we could draw a conclusion that less expression of blood CD4(+) and CD8(+) T cells count might reflect the severity of infection and often accompanied by a poor prognosis. Hence, we inferred blood CD4+ and CD8+ T cells count could be a promising biomarker for disease assessment and monitor of patients with COVID-19.
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spelling pubmed-73199382020-06-29 Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis Hu, Daojun Li, Li Shi, Wenjie Zhang, Li Clin Chim Acta Letter to the Editor This study mainly focused on the very serious COVID-19 epidemic situation at present and provided a new insight for the treatment and monitor of patients with COVID-19. Through this meta-analysis, we could draw a conclusion that less expression of blood CD4(+) and CD8(+) T cells count might reflect the severity of infection and often accompanied by a poor prognosis. Hence, we inferred blood CD4+ and CD8+ T cells count could be a promising biomarker for disease assessment and monitor of patients with COVID-19. Elsevier B.V. 2020-11 2020-06-27 /pmc/articles/PMC7319938/ /pubmed/32598880 http://dx.doi.org/10.1016/j.cca.2020.06.040 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to the Editor
Hu, Daojun
Li, Li
Shi, Wenjie
Zhang, Li
Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis
title Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis
title_full Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis
title_fullStr Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis
title_full_unstemmed Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis
title_short Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis
title_sort less expression of cd4(+) and cd8(+) t cells might reflect the severity of infection and predict worse prognosis in patients with covid-19: evidence from a pooled analysis
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319938/
https://www.ncbi.nlm.nih.gov/pubmed/32598880
http://dx.doi.org/10.1016/j.cca.2020.06.040
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