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Distal lung epithelial progenitor cell function declines with age

Tissue stem cell exhaustion is a key hallmark of aging, and in this study, we characterised its manifestation in the distal lung. We compared the lungs of 3- and 22-month old mice. We examined the gross morphological changes in these lungs, the density and function of epithelial progenitor populatio...

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Detalles Bibliográficos
Autores principales: Watson, Julie K., Sanders, Philip, Dunmore, Rebecca, Rosignoli, Guglielmo, Julé, Yvon, Rawlins, Emma L., Mustelin, Tomas, May, Richard, Clarke, Deborah, Finch, Donna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319976/
https://www.ncbi.nlm.nih.gov/pubmed/32591591
http://dx.doi.org/10.1038/s41598-020-66966-y