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Distal lung epithelial progenitor cell function declines with age
Tissue stem cell exhaustion is a key hallmark of aging, and in this study, we characterised its manifestation in the distal lung. We compared the lungs of 3- and 22-month old mice. We examined the gross morphological changes in these lungs, the density and function of epithelial progenitor populatio...
Autores principales: | Watson, Julie K., Sanders, Philip, Dunmore, Rebecca, Rosignoli, Guglielmo, Julé, Yvon, Rawlins, Emma L., Mustelin, Tomas, May, Richard, Clarke, Deborah, Finch, Donna K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319976/ https://www.ncbi.nlm.nih.gov/pubmed/32591591 http://dx.doi.org/10.1038/s41598-020-66966-y |
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